Monoamine transporters (MATs) are proteins that function as integral plasma-membrane transporters to regulate concentrations of extracellular monoamine neurotransmitters. The three major classes are serotonin transporters (SERTs), dopamine transporters (DATs), and norepinephrine transporters (NETs)
種類[]
dopamine reuptake inhibitor多巴胺再回收抑制劑[]
.
norepinephrine reuptake inhibitor正腎上腺素再回收抑制劑[]
.
serotonin reuptake inhibitor血清素再回收抑制劑[]
.
例子[]
dopamine reuptake inhibitor多巴胺再回收抑制劑和norepinephrine reuptake inhibitor正腎上腺素再回收抑制劑的活性較難分開。SSRI和NSRI常常用來治療憂鬱症和焦慮症
機轉[]
NE會使得大腦興奮，興奮和焦慮是很類似的，使大腦興奮起來加上血清素使心情好的作用使得焦慮的情緒緩和。(參考血管硬化危險指數Chol/HDL)
Selective serotonin reuptake inhibitor（SSRI）[]
Drugs in this class include (trade names in parentheses):
- Fluoxetine(百憂解)
- Citalopram
- Dapoxetine
- Escitalopram
- Fluvoxamine
- Paroxetine
- Sertraline
- Zimelidine
Serotonin-norepinephrine reuptake inhibitor[]
- Tricyclic antidepressants
- NSRIEx. 千憂解
Norepinephrine-dopamine reuptake inhibitor[]
Dopamine reuptake inhibitor[]
- Cocaine
- Amineptine (Maneon, Survector)
- Caffeine
- Bupropion:或分類為 DNRI
- (-)-2-β-Carbomethoxy-3-β-(4-fluorophenyl)tropane naphthalenedisulfonate
- Dextromethorphan
- Methylenedioxypyrovalerone (MDPV)
- Methamphetamine:或促進dopamine釋放
- Methylphenidate:或促進dopamine釋放
- Phenmetrazine
- Vanoxerine
- Venlafaxine
Norepinephrine reuptake inhibitor (SNRI)[]
- Atomoxetine
- Reboxetine
- Viloxazine
- Maprotiline
- Nortriptyline
- Bupropion:或分類為 DNRI
- Radafaxine