Endocarditis

• Aminoglycoside 和Beta-lactam antibiotics一起使用可以增強對G(+)的效用
  • Aminoglycoside are in combination with vancomycin or a penicillins for endocarditis, and for treatment of tuberculosis
    • vancomycin + gentamicin(aminoglycoside) is the alternative of enterococcal endocarditis
  • Penicillins plus Streptomycin is effective for
    • enterococcal endocarditis
    • virdans streptococcal endocarditis
• clindamycin can replace Erythromycin as prophylaxis against endocarditis during dental procedures
• vancomycin main indication: methicillin-resistant staphylococci caused sepsis or endocarditis